Pariet 20 mg is the second generation Proton pump inhibitor

It is an enteric-coated light yellow   tablet , small in size, with rapid onset of  action, containing sodium Rabeprazole.

Pariet 20 mg is used to treat the following diseases:

1- Gastric  ulcers

2- Duodenal ulcer

3- Gastro esophageal reflux disease (GERD)

4- Zollinger-Ellison syndrome

5- H. pylori eradication

6- stomach  sleeve procedures

7- Esophagitis

Pariet 20 mg is characterized by its high efficacy and speed, it has a fast onset of action  which been activated within one hour of taking  the dose  , its efficacy dose not affected by food  . It is the least interacting with other medications, and may be taken with Clopidogrel, warfarin.

Warnings and precautions :

Pariet 20 mg is recommended to be used with caution with the following medications :

Itraconazole, Gefitinip, as the absorption of these drugs requires a high acidity  in the stomach which  interferes with the action of Pariet 20 mg and the doses must be spaced apart.

Recommended dosage:

 1. In cases of GERD

It is recommended to use one tablet  daily in the morning and before food for four weeks

If symptoms persist, the doctor may advise the use of one tablet  when needed

 2.  In cases of stomach ulcers

 It is recommended to use one tablet  per day in the morning before food  for 6 weeks

The doctor may instruct the patient  to continue the treatment for another 6 weeks if the symptoms persist .

 3. In cases of duodenal ulcer

It is recommended to use one tablet  a day in the morning before food  for four continuous weeks

The doctor may instruct the patient  to continue the treatment for another 4 weeks if the symptoms persist

4. In cases of ulcers caused by h. pylori infection

It is advised to be used with other medications (as per the doctor advise ) one tablet in the morning and one  tablet  in the  evening for 7 days

5. In cases of Zollinger-Ellison Syndrome

Treatment begins with three tablet  daily and the doctor increases or decreases the number of daily dose  based on the degree of improvement of the patient and his response to treatment

Warnings and precautions:

Rabeprazole is not recommended if there is any allergy to proton pump inhibitors

Rabeprazole is not recommended for use in patients with blood and liver diseases whose symptoms improve upon discontinuation of proton pump inhibitors.

Rabeprazole is not recommended for patients who use Atazanavir as a treatment for HIV

As a whole, PPI may reduce vitamin B12 absorption

Pregnancy and lactation:

There are no adequate studies, and the decision is referred to the doctor, according to the case based in risk benefits ratio

Patients with liver problems:

Please consult your doctor to assess the condition and determine the appropriate dose

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