MethyCobal 500 Mcg (Tablets) Methycobal tablet is a white sugar coated tablet which contain 500 mcg of mecobalamin, a vitamin B12 – coenzyme which is available in the blood and the cerebrospinal fluid Methycobal is the active form of Vitamin B 12 which taken up by nerve tissue more actively and extensively more than other Vitamin B12 forms Methycobal is the first pharmaceutical product that has shown by double blind clinical studies to be effective and useful for the treatment of numbness, pain & paralysis due to peripheral neuropathy. Indications: 1.Peripheral neuropathies Treat the signs and symptoms of neuropathy due to diabetes or other diseases by acting as Ch3 donor for the trans-methylation process, which has main role for Phospholipid synthesis for mylen sheeth rebuilding In addition, methycobal has a role in protein synthesis, which is required for DNA synthesis inside the cell to help nerve axon rebuilding Dosage and administration: The usual daily dose for adults is 3 tablets administrated orally in 3 divided doses equivalent to 1500 mcg of mecobalamin General precautions: Methycobal should not be administered for extensive periods ( months ) to patients who show no clinical response. Other precautions: Prolonged use of larger doses of methycobal is not recommended for patients whose occupation requires handling mercury or its compounds. Adverse reaction: - Gastrointestinal symptoms like nausea and diarrhea may infrequently occur - Dermatological skin rash may rarely occur Pregnancy and lactation: There are no adequate studies, and the decision is referred to the doctor, according to the case based in risk benefits ratio Premium quality product manufactured by Eisai Japan .